Current opinion on micro- and nanoplastics

Thematic journal issue on micro- and nanoplastics addresses sources, fate, human health and environmental effects, sampling methods, research needs

Alternative plasticizers adipogenic in vitro

Several alternative plasticizers used in FCMs shown to promote lipid accumulation in vitro; direct activation of PPARγ suggested as possible mechanism

Assessing risks of hydrophobic chemicals

Scientists argue that water-focused assessment schemes may misjudge risks of hydrophobic chemicals; sediments, particles, exposure through diet additionally play an important role; contribution of microplastics and nanoplastics uncertain but likely low

Androgens may predispose to autism

Scientists show that androgens regulate key genes linked to autism risk and may contribute to excessive brain growth, suggest that androgens’ effects on developing brain may increase risk of developing autism spectrum disorders

Common food contact chemical causes reproductive failure

Scientists demonstrate migration and sperm-related reproductive toxicity of surfynol, a surfactant commonly used in adhesives employed in multilayer food packaging

BPA labeling in foods and food packaging ‘inadequate’

‘Real-world’ dietary intervention study highlights inadequate labeling as a barrier to following individual-focused strategies aimed at reduction of dietary BPA exposure

Definition of nanoplastics

Scientists propose defining nanoplastics as unintentionally produced particles sized between 1 to 1000 nm and exhibiting colloidal behavior, discuss future research needs

Shorter-chain PFCs may persist in human tissues

Researchers estimate internal exposure to metabolites of shorter-chain polyfluorinated compounds, demonstrate high potential for biopersistence, call for further research

Migration of nitrosamines from FCMs

Scientists develop analytical method to measure N-nitrosamines migrating from elastomeric food contact materials; 6 nitrosamines detected frequently; BfR-recommended limit exceeded for one styrene block copolymer sample

BPA and analogues: Multiple targets and effects

Scientists highlight BPA’s interactions with multiple molecular targets besides estrogen receptor; growing body of evidence demonstrates similar pleiotropic actions of BPA substitutes such as BPS, BPF, BPAF and others