Extranuclear actions of EDCs at low doses

Scientists review molecular mechanisms underlying low-dose actions of estrogenic EDCs, focusing on extranuclear signaling; BPA effects in pancreas and heart mediated through alpha-, beta-, and membrane-associated forms of estrogen receptor

BPA disrupts regulation of feeding behavior

Scientists show that exposure to low-dose BPA during fetal development interferes with leptin and hypothalamic feeding circuitry, disrupts regulation of feeding behavior, predisposes to obesity in later life

Guidelines for sample preparation needed

EU Commission’s Joint Research Centre publishes study on heavy metal contamination in canned vegetables, shows need for clear sample preparation guidelines to ensure harmonized compliance assessment

AOP-based computational models for regulatory toxicology

Review article by EU Commission’s Joint Research Centre and collaborators discusses development and use of computational prediction models for regulatory toxicology and how it can be supported by the Adverse Outcome Pathways framework

Predicting mutagenicity of chemicals in printed paper and board FCM

Scientists propose a strategy for prioritizing assessment of non-evaluated chemicals potentially present in printed paper and board FCM with help of quantitative structure-activity relationship (QSAR) models; identify 106 substances of highest concern

Strategy for less animal testing

Swedish Chemicals Agency publishes report on the replacement, reduction and refinement of animal experiments to assess chemical safety

Children exposed to lead from water and food

Formula-fed infants and toddlers in U.S. exposed to lead mainly from water and food, respectively, according to new report by Environmental Protection Agency

EFSA working group on recycling plastics: 15th meeting

Updated meeting minutes of EFSA’s CEF Panel working group on recycling plastics now available online

EFSA reevaluation of BPA: 3rd meeting

EFSA’s CEF Panel Working Group on BPA assessment protocol holds third meeting on the safety reevaluation of BPA; meeting minutes available online

FPF can coatings webinar: Video online

Food Packaging Forum held webinar on can coatings on February 7, 2017; video recording now available