Linking chemical exposures to birth outcomes: Insights from the ECHO Program

Two studies use Environmental influences on Child Health Outcomes (ECHO) Program in the US to investigate chemical exposures and birth outcomes; several phthalates associated with decreased gestational age, increased risk of preterm birth; ~56,595 preventable preterm births and $3.84 billion healthcare costs in US annually

Unexpected SVHC phthalate metabolite found in humans, including children

German biomonitoring study finds mono-n-hexyl phthalate in majority of samples, indicating widespread exposure to substance of very high concern (SVHC) di-n-hexyl phthalate or related compounds; sources of exposure currently under investigation; contribution of food contact materials to human exposure possible, but only limited data available

Minderoo Foundation systematically maps human health effects from plastic-associated chemicals

Interactive and openly available, the Plastic Health Map summarizes human health outcomes of certain plastic-associated chemicals and particles as published by peer-review articles between 1960 and 2021; includes more than 3500 studies for 1557 chemicals; identifies gaps, including only 30% of chemicals have been investigated for health impacts, few studies in low-income countries

Phthalates: impact on leiomyoma growth and mixture risk

Study identifies mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) exposure as high-risk factor for leiomyoma growth on epidemiological and mechanistic level; European biomonitoring of five reprotoxic phthalates demonstrates necessity to integrate mixture risk assessment into regulatory practice; targeted analysis shows migration of five phthalates from polypropylene food packaging

Microplastics in humans: current knowledge and potential implications

Review summarizes microplastics abundance and characteristics in human biological samples including current research approaches employed, challenges, and prospects; study indicates microplastics impact human meconium and placenta microbiota; review outlines current evidence on microplastic effects upon exposure during early developmental stage

Microplastic exposure through drinking cups and human health impacts

Study finds up to 6000 particles/L to be released from disposable drinking cups; scientists estimate humans ingest 37,613–89,294 microplastics through plastic cups use per year; study suggests consumption from plastic containers changes human gut and oral microbiota composition; review concludes that uptake of microplastics carrying pathogens may impact human health

Biomonitoring provides insights into nonylphenol exposure in Germany

Retrospective analyses of urinary nonylphenol (NP) levels in German students over past 30 years demonstrate omnipresence of NP exposure; scientists recommend using NP metabolites as biomarkers for NP exposure assessment; analysis points to foodstuff as major exposure source

Scientists explore international bisphenol levels in packaging, food, and urine

Four studies investigate bisphenol (BP) migration from packaging, occurrence in foodstuff, and human urine; report BPA migration from Nigerian epoxy-coated cans into malt drinks; detect four bisphenols in packaged water and honey samples; find BPS in Canadian meat products from 2008 to 2020 suggesting BPS is not a recent phenomenon; measure higher bisphenol alternative levels in Belgian population in 2018 than 2015

Studying phthalates: Linkage with dietary habits and molecular changes

Biomonitoring finds regular takeaway food consumption increases phthalate exposure; intervention study links plastic packaged hot soup consumption with increased phthalate exposure and changes in mRNA expression of inflammatory cytokines; structural analysis suggests non-phthalate alternative plasticizers have potential for thyroid hormone disruption

2021 FPF Workshop: Proceedings available

9th annual Food Packaging Forum workshop brings stakeholders from different fields together to discuss the latest science, policy, and stakeholder collaboration across the field; presentation videos, slides, and summary articles now available