European Commission publishes proposal to amend Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures (CLP); aims to define identification criteria of chemical health hazards, communication of those hazards, and enforcement
Phthalates: impact on leiomyoma growth and mixture risk
Study identifies mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) exposure as high-risk factor for leiomyoma growth on epidemiological and mechanistic level; European biomonitoring of five reprotoxic phthalates demonstrates necessity to integrate mixture risk assessment into regulatory practice; targeted analysis shows migration of five phthalates from polypropylene food packaging
Chemicals used to produce PET cause cells to store fat, say scientists
Study investigate correlation of starting substances to manufacture polyethylene terephthalate (PET) with obesity; report these para-phthalates to alter adipogenesis in vitro at nanomolar concentrations; consider ascertaining their safe levels a high priority
Bioassays can help to develop safer food packaging
In vitro study assesses hormonal activity of leachates from bio-based polymers used in food packaging; demonstrates integration of toxicity testing in packaging development can help reduce toxicity and design safer bio-based packaging
2022 FPF Workshop: FCM developments in the last decade
On the morning of the Food Packaging Forum’s annual workshop, speakers discuss changes in food contact material (FCM) regulation in the EU, US, and Asia; panels discuss key research and policy developments over the last decade
Beyond BPA – Many bisphenols migrate from food packaging
Four studies investigate bisphenol (BP) migration from food packaging and human health effects; demonstrate wide presence of 11 bisphenols in polystyrene take-out food containers from China, Canada, and Poland; report material quality influences BPA migration from polycarbonate cups; indicate higher BPA migration from lined cans than plastic packaging into meat based on probabilistic models; find bisphenols A, F, and S induce genotoxic effects and changes in human endogenous retroviruses (HERVs) expression using human blood cells
Arguments by PlasticsEurope in BPA case “unfounded,” says Advocate General
EU Advocate General advises the General Court to reject the primary argument of PlasticsEurope in its case against the European Chemicals Agency’s (ECHA) identification of bisphenol A (BPA) as a substance of very high concern (SVHC); Advocate General calls the argument “in its entirety as unfounded”; this appeal is based on the classification as an environmental endocrine disruptor
Viewpoint: Subthreshold effects need consideration in chemical risk assessment
Scientists point out chemical risk assessments worldwide neglect current scientific knowledge; advocate to consider potential subthreshold effects in regulatory risk assessment
Scientists identify food packaging as organophosphate ester source
Scientists establish organophosphate esters (OPEs) baseline concentration in foodstuff across China and investigate the contamination sources; report extensive contamination of Chinese foodstuff with OPEs; uncover food packaging as source of these OPEs
Studying phthalates: Linkage with dietary habits and molecular changes
Biomonitoring finds regular takeaway food consumption increases phthalate exposure; intervention study links plastic packaged hot soup consumption with increased phthalate exposure and changes in mRNA expression of inflammatory cytokines; structural analysis suggests non-phthalate alternative plasticizers have potential for thyroid hormone disruption