Interactive and openly available, the Plastic Health Map summarizes human health outcomes of certain plastic-associated chemicals and particles as published by peer-review articles between 1960 and 2021; includes more than 3500 studies for 1557 chemicals; identifies gaps, including only 30% of chemicals have been investigated for health impacts, few studies in low-income countries
Synergistic interaction in real-life mixtures might not be so rare, scientist finds
“How frequent is rare?” researcher asks, emphasizes that based on current knowledge it is “premature” to neglect chemical synergism in real-life mixtures due to being “rare” and limit focus to additive behavior of chemicals; calls for further research and considering synergism in debates on mixtures risk assessment
Scientists recommend policy actions to reduce EDC health impacts
Review describes how cost and disease burden of endocrine-disrupting chemicals (EDCs) can be reduced by policy actions informed by science; recommended solutions include updating testing to account for mixture, cumulative exposure, effects occurring later life; second review summarizes studies linking EDC exposure with immunological and metabolic impacts during pregnancy
Phthalates: impact on leiomyoma growth and mixture risk
Study identifies mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) exposure as high-risk factor for leiomyoma growth on epidemiological and mechanistic level; European biomonitoring of five reprotoxic phthalates demonstrates necessity to integrate mixture risk assessment into regulatory practice; targeted analysis shows migration of five phthalates from polypropylene food packaging
Scientists present and apply spectral database on plastic additives
Researchers develop high-resolution spectral database and method for the identification of 56 selected organic plastic additives; indicates presence of multiple additives when applied to polypropylene and polylactic acid food packaging; highlight chemical signature not polymer but product dependent and “bioplastic” just as conventional plastics contain harmful additives
Study identifies chemicals driving semen quality deterioration
Scientists perform mixture risk assessment on 29 chemicals capable of affecting semen quality; show exposure to chemicals that lead to declined semen quality highly exceed tolerable daily intake in Europe; identify bisphenols, polychlorinated dioxins, paracetamol, and phthalates as risk drivers
Commentary on chemical pollution calls for prioritizing health
Author describes the planet’s chemical legacy and emphasizes need for targeted global approach to contend with chemical pollution
Systematic review finds evidence “robust” that BPA reduces semen quality
Scientists review the association between bisphenol A (BPA) exposure and declines in semen quality based on animal and epidemiological studies; assess weight of evidence of associations and estimate BPA reference dose of 0.003 µg/kg/d for male reproductive health for use in mixture risk assessments
Public consultation on REACH review
European Commission (EC) opens a public consultation period concerning the revision of REACH regulation; REACH is responsible for outlining chemical assessment procedures in the EU; possible updates include assessing chemical mixtures, simplifying safety data sheets, and incorporating essential-use concept; consultation period open until April 15, 2022
2021 FPF Workshop: Proceedings available
9th annual Food Packaging Forum workshop brings stakeholders from different fields together to discuss the latest science, policy, and stakeholder collaboration across the field; presentation videos, slides, and summary articles now available