AOPs in Integrated Approaches to Testing and Assessment of chemicals

OECD publishes guidance on the use of Adverse Outcome Pathways (AOPs) in developing Integrated Approaches to Testing and Assessment (IATA); AOPs to support chemical grouping, development of models, test methods, and testing strategies, and interpretation of test results

Conference report: Towards a non-toxic future

Stakeholder conference held by Danish Ministry delivers recommendations for future EU chemicals regulation; conference report now available

EFSA: Consultations on weight of evidence and biological relevance

EFSA announces public consultation on two draft guidance documents concerning use of weight of evidence approach in scientific assessments and identification of biological relevance of observed effects

Fully embedded nanoparticles do not migrate

Scientists review experimental and modeling studies on migration of nanoparticles from food contact plastics; conclude that no migration will occur if nanoparticles are fully embedded in polymer; mechanical stress or damage could lead to increased release

Fluorene-9-bisphenol is anti-estrogenic

Scientists examine occurrence and effects of bisphenol A substitute, fluorene-9-bisphenol (BHPF); BHPF present in about half of ‘BPA-free’ bottles; BHPF is anti-estrogenic, causes smaller wombs, miscarriages, and smaller pups in mice

FPF Workshop 2017: Save the date!

Food Packaging Forum holds 5th annual workshop on October 5, 2017 in Zurich, Switzerland; first speakers and topics announced

EFSA: Survey on uncertainty in risk assessment

EFSA runs survey on communication of uncertainty in scientific risk assessments

Lack of ‘nano’ in OECD nanomaterials dossiers

NGO-commissioned study finds that OECD’s dossiers on 11 nanomaterials are of ‘little to no value’ in assessing risks; characterization of test materials in most cases ‘insufficient’ to ensure nano-specificity

IARC replies to critiques

IARC scientists reply to critical commentary; point out the importance of hazard classification as an initial step in the risk assessment process, highlight the role of epidemiological evidence

Academic research vs. guideline studies

Article in Science illustrates gap between academic researchers and regulators about scientific evidence use in assessment of chemicals’ health risks