Scientists explore international bisphenol levels in packaging, food, and urine

Four studies investigate bisphenol (BP) migration from packaging, occurrence in foodstuff, and human urine; report BPA migration from Nigerian epoxy-coated cans into malt drinks; detect four bisphenols in packaged water and honey samples; find BPS in Canadian meat products from 2008 to 2020 suggesting BPS is not a recent phenomenon; measure higher bisphenol alternative levels in Belgian population in 2018 than 2015

What knowledge is missing to derive a microplastic threshold value?

Microplastic experts review mammalian in vivo effect studies and develop non-regulatory health-based screening level value for microplastics in drinking water; scientists provide research recommendations to better understand microplastic toxicity, effect levels, and potential health risks to humans and aquatic ecosystems; review discusses nanoplastics’ role in food allergy

Study identifies chemicals driving semen quality deterioration

Scientists perform mixture risk assessment on 29 chemicals capable of affecting semen quality; show exposure to chemicals that lead to declined semen quality highly exceed tolerable daily intake in Europe; identify bisphenols, polychlorinated dioxins, paracetamol, and phthalates as risk drivers

Review on EDCs and breast cancer calls for research inclusivity

Researchers review association between endocrine-disrupting chemical (EDC) exposure, specifically per- and polyfluoroalkyl substances (PFAS) and parabens, and breast cancer development; report structural racism increases EDC exposure of marginalized communities; emphasize need for considering socially disadvantaged populations in research to mitigate exposure and improve breast cancer disparities; review finds bisphenol A (BPA) replacements BPS and BPF as carcinogenic as BPA

Systematic review finds evidence “robust” that BPA reduces semen quality

Scientists review the association between bisphenol A (BPA) exposure and declines in semen quality based on animal and epidemiological studies; assess weight of evidence of associations and estimate BPA reference dose of 0.003 µg/kg/d for male reproductive health for use in mixture risk assessments

Researchers associate diet and microplastics with EDC exposure

Epidemiological studies investigate association between diet and endocrine-disrupting chemical (EDC) exposure; find recommended healthy diets not protective against EDC exposure; report association of plastic-free diet with reduced urinary bisphenol A (BPA) in children; researchers performing bioaccessibility tests using gut fluids find release of phthalates and BPA from microplastics may pose human health risk

Microplastics: linkage to the gut’s microbiome and autism spectrum disorder

Scientific study reports that gut passages change polyethylene terephthalate (PET) microplastics morphology and alter human microbial colonic community composition; another study finds polyethylene (PE) microplastics to accumulate in the brain and induce autism spectrum disorder-like symptoms using a mouse model

Microplastic impacts on child health: knowns and unknowns

Scientific commentary discusses pregnancy- and child-relevant exposure to and impacts of nano- and microplastics: finds 37 studies mostly on plastic particles in food and placental transfer, identifies major knowledge gaps, and advocates policymakers and industry to implement precautionary approaches; Nature Reviews Materials article proposes microplastic risk assessment framework

Multi-criteria framework to prioritize polymers of concern

Scientists develop holistic conceptual framework to characterize and rank the environmental risks of plastic polymers; tool can support targeted investment and mitigation strategies

Scientists explore effects of micro- and nanoplastics on mammals, including humans

Research studies show maternal polystyrene (PS) particle exposure can cause testicular and hepatic toxicity in male mouse offspring; report PS microplastics affect rat ovary function; find correlation between human fecal microplastics levels and Inflammatory Bowel Disease; reviews summarize potential human health effects; study develops a tool to screen and prioritize micro-and nanoplastics toxicity studies for human health risks evaluation