Controversy over DINCH

McGill university study shows exposure of pregnant rats to DINCH results in liver metabolism impairment and ‘testicular atrophy’ in the male progeny; BASF scientists depict study as ‘flawed,’ maintain that DINCH is safe for use in food contact applications

ANSES: Not enough data on TMBPF

ANSES finds insufficient data to conclude on the potential endocrine disrupting properties of tetramethylbisphenol F (TMBPF), a bisphenol A alternative

FPF Workshop 2017: Toxicological assessments and migration testing

Experts from academia, food industry and authorities present scientific and practical challenges in toxicological assessments and migration measurements

FCMs, gut health and risk assessment

New scientific article reviews food contact chemicals’ effects on gut permeability, microbiota, and immune responses; scientific justification for risk assessment assumptions questioned

Melamine’s effects beyond kidney

Scoping review identifies potential health effects of melamine other than renal damage, including impacts on neurological functions, behavior, reproduction, and growth

Utility of bioassays in safety assessment

Scientists demonstrate utility of bioassays in FCM safety assessment using 4-nonylphenol (4NP) as model substance; 4NP levels detected by bioassays considered relevant for safety assessment

High throughput in vitro testing of BPA analogues

Scientists analyze estrogen- and androgen-like properties of BPA analogues using cell-based high throughput microscopy-employing tests; demonstrate anti-estrogenic and anti-androgenic properties of TMBPF

In vitro testing of FCMs: Current science and future challenges

New scientific study by FPF summarizes research on alternative toxicity testing of FCMs, finds approach promising and feasible; sample preparation methods need to be optimized and standardized; employed assays should be of clear human health relevance

Phthalates’ impact on human health

Scientists compile comprehensive review on phthalates, focus on human health effects observed in epidemiological and clinical studies

Genotoxic chemicals in coatings

Scientists compile inventory of compounds potentially used in coatings; 1,976 substances have no (recent) toxicological evaluation; subset analyzed by in silico tools and literature search, 10 compounds designated as ‘high concern’