In a new study published on July 30, 2013 in the peer-reviewed scientific journal Human Reproduction, researchers from Brigham and Women’s Hospital (BWH), Boston, U.S. showed that in vitro bisphenol A (BPA) exposure disrupts human egg maturation. Machtinger and his colleagues exposed 352 eggs from 121 consenting patients at a fertility clinic to various doses of BPA in the nano- and microgram per milliliter solution range. One unexposed egg per patient served as a control. The researchers found that BPA exposure decreased the percentage of eggs maturing, increased the percentage of eggs degenerating and increased the percentage of eggs undergoing spontaneous activation. In an article published July 31, 2013 with the online science news publisher Science Daily, Catherine Racowsky, director of the Assisted Reproductive Technologies Laboratory at BWH and co-author of the study stated that further research should be conducted in order to better understand the role of BPA in infertility.
Machtinger, R. et al (2013). "Bisphenol-A and human oocyte maturation in vitro.” Human Reproduction (published online July 30, 2013).