In a perspective article published on July 20, 2018 in the peer-reviewed journal Science, two scientists call for “ensuring appropriate regulation of chemical mixture risks.”

Andreas Kortenkamp from the Institute of Environment, Health and Societies, Brunel University London, UK, and Michael Faust from the Faust & Backhaus Environmental Consulting, Bremen, Germany, observe that “humans and wildlife are continuously exposed to multiple chemicals from different sources and via different routes, both simultaneously and in sequence.” Despite the scientific evidence that toxicity from such mixtures is “heightened,” the regulation is “lagging behind.”

Therefore, Kortenkamp and Faust call for “stronger legal stimuli as well as close integration of different parts of the regulatory systems in order to meet the data and testing requirements for mixture risk assessment.”


Andreas Kortenkamp and Michael Faust (2018). “Regulate to reduce chemical mixture risk.Science 361: 224-226.