A new study published online on February 13, 2015 in the peer-reviewed journal Environmental Science & Technology looks at the occurrence of bisphenol A diglycidyl ether (BADGE, CAS 1675-54-3) and bisphenol F diglycidyl ether (BFDGE, CAS 2095-03-6) in adipose fat and plasma. BADGE and BFDGE are used in the protective coatings of cans and in paints and adhesives. As knowledge about human exposure to these substances is very limited, Wang and colleagues measured BADGE and BFDGE and seven of their derivatives in human adipose fat and blood plasma samples collected in New York, U.S.. The authors also determined bisphenol A (BPA, CAS 80-05-7) levels in these samples to investigate its association with BADGE and BFDGE. BADGE was found in 25% of the adipose samples and none of the plasma samples. However, its hydrolyzed derivative BADGE▪2H2O, was detected in 60% of the adipose samples and 70% of the plasma samples. BFDGE was found in high quantities in all adipose and plasma samples. The positive correlation between BADGE and its derivatives (BADGEs) and BFDGE and its derivatives in adipose samples points to similar human exposure sources and pathways for these compounds. BPA concentrations were also positively correlated with those of BADGEs, thus confirming co-exposure of BADGEs and BPA in humans.
Wang, L. et al. (2015). “Widespread occurrence and accumulation of bisphenol A diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE) and their derivatives in human blood and adipose fat.” Environmental Science & Technology (published online February 13, 2015).