On December 18, 2017, the European Food Safety Authority (EFSA) published a scientific opinion clarifying how it “evaluates the potential genotoxicity of substances in food and feed assessments.”

In an accompanying press release, Anthony Hardy, chair of EFSA’s Scientific Committee, explained that the new document “provides recommendations on the adequacy of specific tests to establish the genotoxic potential of substances.” Further, it gives “advice on using data in weight-of-evidence approach to conclude on genotoxicity and whether or not it is possible to set safe levels for substances.” Hardy further noted that this publication “improves clarity and predictability for applicants [preparing dossiers],” and helps both risk assessors and risk managers “when deciding on the approval or restriction of substances in the food chain.”

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EFSA (December 18, 2017). “Update on how EFSA evaluates genotoxicity.


EFSA (December 18, 2017). “Clarification of some aspects related to genotoxicity assessment.EFSA Journal 15(12):5113.