On December 2, 2015 the EU Reference Laboratory for food contact materials (EURL-FCM) of the European Commission’s (EC) Joint Research Centre (JRC) published a report providing practical guidance on migration modeling for estimation of specific migration. In particular, the report focuses on “diffusion models to predict conservative, upper bound specific migration values from plastic food contact materials for compliance purposes.” It includes estimation methods for diffusion coefficients, polymer specific parameters, partition coefficients, and other model input parameters, as well as practical applications and examples. This report replaces the previous guidance document entitled “Estimation of specific migration by generally recognised diffusion models in support of EU Directive 2002/72/EC” and updates to the current legal basis (plastic FCM Regulation (EU) No 10/2011).
Hoekstra, E. et al. (2015). “Practical guidelines on the application of migration modelling for the estimation of specific migration.” JRC EURL-FCM (pdf)