The British study carried out by Maisonet et al. (2012) was able to link maternal concentrations of perfluorooctane sulfonate (PODS), perluorooctanoate (PFOA) and perfluorohexane sulfonate (PFHxS) to fetal and postnatal growth in girls. The study compared the upper tertile to the lower tertile and found girls in the upper tertile to weigh 140g less at birth than those in the lower tertile. At twenty months the association reversed with girls in the upper tertile weighing 580 g more than girls in the lower tertile. The study also associated PFC exposure with reduced birth length. Perfluorinated compounds are used in food packaging materials, for example in non-stick paper coating. 448 girls with at least two valid pubertal status assessments and their mothers were examined. The study confirmed observations that had been previously made in animal studies.


Maisonet, M. et al. (2012). Maternal Concentrations of Polyfluoroalkyl Compounds during Pregnancy and Fetal and Postnatal Growth in British Girls. Environmental Health Perspectives 120(10): 1432–1437. Published online 2012 August 30. doi: 10.1289/ehp.1003096

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