In an article published on October 31, 2018, the National Food Institute of the Technical University of Denmark (DTU Food) informed about a project on suspected endocrine disrupting chemicals (EDCs) that was conducted by researchers from DTU Food and the University of Southern Denmark (SDU). Ulla Hass and colleagues compiled a priority list of 172 suspected EDCs and reviewed the scientific literature for 52 selected substances. 13 substances were then further prioritized and evaluated according to the EU criteria for identifying EDCs in the field of biocides and pesticides (FPF reported).
As a result, the researchers identified nine substances that can be considered EDCs based on the EU criteria. The substances are: 1) Prochloraz (CAS 67747-09-5), 2) triclocarban (CAS 101-20-2), 3) octamethylcyclotetrasiloxane (D4, CAS 556-67-2), 4) tris(methylphenyl) phosphate (CAS 1330-78-5), 5), salicylic acid (CAS 69-72-7), 6) fenitrothion (CAS 122-14-5), 7) di-n-pentylphthalate (CAS 131-18-0), 8) bisphenol AF (BPAF, CAS 1478-61-1), and 9) isobutyl paraben (CAS 4247-02-3).
Salicylic acid is included in the Union List of substances authorized for use in plastic food contact materials (FCMs) (Annex I of Regulation (EU) No 10/2011), the ESCO working group list of non-plastic FCMs, and the FACET inventory of FCMs. D4 is also included in the FACET list and was added to the REACH Candidate List of substances of very high concern (SVHCs) due to its very persistent and very bioaccumulative (vPvB) as well as persistent, bioaccumulative and toxic (PBT) properties in June 2018 (FPF reported). BPAF may currently be used as a replacement chemical for bisphenol A (BPA, CAS 80-05-7) (FPF reported). BPA is included in the Union, ESCO, and FACET lists as well as in the Candidate List of SVHCs due to its reprotoxic and endocrine disrupting properties (FPF reported).
Miriam Meister (October 31, 2018). “Nine ‘new’ endocrine disrupting chemicals identified.” DTU Food
Hass, U., et al. (September 2018). “List of endocrine disrupting chemicals.” Danish Centre on Endocrine Disrupters (pdf)