Laura N. Vandenberg from the Department of Public Health at the University of Massachusetts at Amherst, U.S. reviews recent finding on low-dose effects of both hormones and endocrine disrupting chemicals (EDCs) in her book chapter on “Low-Dose Effects of Hormones and Endocrine Disruptors”, published in January 2014 in the 94th volume of Vitamins and Hormones. The author retraces scientific developments in endocrinology and refers to insights on low-dose effects of EDCs. Even though research in the field of low doses is not undisputed, with opponents negating any low-dose effect, consensus has been reached among major parts of the scientific community and recently also institutions such as the Endocrine Society and the World Health Organisation (WHO). Based on the available knowledge, the latter emphasizes that national health authorities include low-dose effects of EDCs into their chemical risk assessment with high priority. Vandenberg furthermore states that a standardized testing setup has to be established in order to guarantee the reproducibility of findings concerning low-dose effects. As for now, divergent results are produced due to incoherent testing parameters, partly fostering the dispute on the reality of EDC low-dose effects.

FPF report “Review on low-dose effects of hormones and EDCs