On December 12, 2014 the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) announced a launch of a new database of Ames positive chemicals. The Ames test is a bacteria-based assay that can be used to predict in vivo mutagenicity of a substance. The EURL ECVAM, operated by the European Commission’s Joint Research Centre (JRC), collected data on 726 Ames positive compounds from various sources. The resulting database is intended to help in the development and evaluation of animal-free testing. The database is to be considered a living project hence can be updated and expanded in the future. It is linked to two other JRC databases, namely CHEList and CHemAgora (previously reported on by the FPF).

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EURL ECVAM (December 12, 2014). “JRC launches the EURL ECVAM genotoxicity & carcinogenicity database of Ames positive chemicals.

EURL ECVAM (December 12, 2014). “EURL ECVAM genotoxicity & carcinogenicity consolidated database of Ames positive chemicals.