According to a new study published in the peer-reviewed scientific Journal of Clinical Endocrinology & Metabolism, exposure to perfluorinated compounds (PFCs) may spark metabolic changes in overweight children (Timmermanns et al. 2014). The Endocrine Society, publisher of the journal, issued a press release on February 25, 2014 stating that this may have an impact on the risk of heart disease. The findings are based on cross-sectional data collected in 1997 as part of the European Youth Heart Study. The researchers analyzed the effects of perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) plasma levels on metabolic markers. Highly exposed overweight children also had higher levels of insulin and triglycerides, which are considered markers of the metabolic syndrome. The association was not observed in normal-weight children.

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Endocrine Society (February 25, 2014). “PFC exposure may spark metabolic changes in overweight children.


Timmermanns, C.A. et al. (2014). “Adiposity and glycemic control in children exposed to perfluorinated compounds.Journal of Clinical Endocrinology & Metabolism (published online February 25, 2014).