In an article published in the September 2015 issue of Environmental Factor, writer Virginia Guidry reports on the “Halifax Project: Low dose theory symposium” that took place on August 25, 2015 at Research Triangle Park, North Carolina, U.S. (FPF reported). In the scope of the Halifax Project, 174 scientists assessed the carcinogenic potential of low-dose exposures to chemical mixtures for 85 chemicals not considered carcinogenic to humans (FPF reported).
The aim of the symposium, hosted by the National Institute of Environmental Health Sciences (NIEHS), was to develop a hypothesis regarding the link between low-dose exposure to chemical mixtures and the development of cancer. Attendees included researchers from government, academia, industry, and non-governmental organizations, as well as from the Halifax Project. They were split up into three roundtable discussion groups on 1) information gaps in the theory of low-dose mixture contribution to carcinogenesis, 2) key research methodologies to enable testing of the hypothesis, and 3) potential implications of low-dose mixture theory on policy and decision-making, as well as potential influence on disease endpoints other than cancer. Participants agreed that an important next step is to generate data to test the low-dose mixtures theory and that transdisciplinary collaborations are essential to future research.
Virginia Guidry (September 2015). “Low-dose mixtures and cancer highlighted at NIEHS symposium.” Environmental Factor