In an article published on December 4, 2017 by the scientific journal Environmental Health Perspectives (EHP), journalist Lindsey Konkel reported on a study investigating co-exposure effects for bisphenol A (BPA, CAS 80-05-7), triclosan (CAS 3380-34-5), and tetrabromobisphenol A (TBBPA, CAS 79-94-7) in mice. The peer-reviewed study was conducted by Tyler Pollock and colleagues from McMaster University, Canada, and published in EHP on August 21, 2017. In April 2017, these researchers published a study focusing on co-exposure effects of parabens and BPA (FPF reported).
At certain doses, the presence of TBBPA in the mice resulted in increased BPA concentrations in several tissues after dietary exposure. Similarly, combined exposure to TBBPA and triclosan significantly increased BPA concentrations in some tissues. “What we see is that each chemical can significantly alter the other chemical’s toxicokinetics, “ Pollock stated. “This study demonstrates the limitations of a single-chemical approach in estimating the impact of chemical exposures on public health,” Konkel thus concluded.
Lindsey Konkel (December 4, 2017). “Compound interest: Assessing the effects of chemical mixtures.” EHP
Pollock, T, et al. (2017). “Influence of tetrabromobisphenol A, with or without concurrent triclosan, upon bisphenol A and estradiol concentrations in mice.” EHP (published August 21, 2017).