On May 26, 2020, the Food Packaging Forum held a webinar featuring a presentation from Anna Soto and Maël Montévil from Tufts University in the US on the observed non-monotonic dose-response of the substance bisphenol A (CAS 80-05-7). The researchers presented and discussed their results recently published in the peer-reviewed journal Environmental Health Perspectives (EHP), which found a consistent pattern of non-monotonic dose-response relationships in rats between BPA exposure and mammary gland development (FPF reported). The study was carried out within the Consortium Linking Academic and Regulatory Insights on Bisphenol-A (CLARITY-BPA) investigating the chemical, which is widely used in the production of resins applied to food contact materials (FCMs). The recorded webinar and accompanying slides are now available.
Food Packaging Forum (May 26, 2020). “Non-monotonicity of BPA.”
Montévil, M. et al. (May 20, 2020). “A Combined Morphometric and Statistical Approach to Assess Nonmonotonicity in the Developing Mammary Gland of Rats in the CLARITY-BPA Study.” Environmental Health Perspectives