Upcoming FPF webinar on novel bioassays for FCMs

On June 30, 2020, the Food Packaging Forum (FPF) will hold a webinar featuring a presentation from Alan Bergmann from the Swiss Centre for Applied Ecotoxicology on recent research developing novel bioassays to improve testing of food contact materials (FCMs); method improves sensitivity of detecting estrogenicity within complex mixtures of chemicals

EFSA: Public consultation on assessing chemical mixtures

EFSA releases draft guidance documents on risk and genotoxicity assessment of chemical mixtures; public consultations open until September 15 and September 9, 2018

Plastic use and exposure to estrogenic chemicals

U.S. pilot study asks participants to reduce plastic use related to food purchase, preparation, storage; blood samples indicate decrease in total estrogenic activity after changing plastic use behavior

ANSES: Not enough data on TMBPF

ANSES finds insufficient data to conclude on the potential endocrine disrupting properties of tetramethylbisphenol F (TMBPF), a bisphenol A alternative

High throughput in vitro testing of BPA analogues

Scientists analyze estrogen- and androgen-like properties of BPA analogues using cell-based high throughput microscopy-employing tests; demonstrate anti-estrogenic and anti-androgenic properties of TMBPF

DEHP increases BPA exposure

Scientists show that diethylhexyl phthalate (DEHP) leads to higher accumulation of bisphenol A (BPA) in reproductive tissues of mice, likely due to competition for detoxification enzymes

Estrogenic activity of BPA alternatives

Study assesses estrogenicity of bisphenol A and 6 bisphenol analogues in human breast cancer cell model; all bisphenols show estrogenic activity; 3 bisphenols more potent than BPA

Summary on estrogenic chemicals and reproductive health

PLOS Biology article highlights reproductive health impacts of estrogenic chemicals such as bisphenol A, its analogues, and phthalates

Epidemiology of mixtures: Xenoestrogens and breast cancer

Scientists find strong association between breast cancer risk and total burden of xenoestrogens; in contrast, individual compounds show only weak associations, if any

Court battle over estrogenicity of BPA-free plastic

Updated report on legal battle involving Tritan® plastic marketed as “EA-free”