11th BioDetectors conference addresses use of cell-based bioassays in food contact material safety analysis
September 7, 2018
Mechanistic data in hazard assessment
Academic and industry scientists debate whether use of mechanistic data in regulatory hazard assessment of chemicals should be decisive or supportive only, discuss study selection process for systematic reviews
March 16, 2018
Progress in high-throughput in vitro testing
In vitro assays and alternative approaches being developed for EPA’s Endocrine Disruptor Screening Program and within EU-ToxRisk are hitting ground
March 9, 2018
Alternative toxicity testing in the U.S.
U.S. EPA publishes draft strategy for use of alternative toxicity tests in evaluation of chemicals under updated chemicals regulation
January 19, 2018
In vitro tests for toxicological profiling of FCMs
In vitro assays demonstrate significant biological activity in extracts from diverse food contact articles made of paper and board; bioassays expected to become accepted tool for assessment of FCM safety
January 12, 2018
Microbiome and chemical risk assessment
U.S. National Academy of Sciences’ report outlines research strategy to assess the need for chemical risk assessments to consider interactions between chemicals and microbiota when estimating human health effects
November 29, 2017
Regulatory status of non-animal approaches
U.S. NAS workshop suggests comparing non-animal tests to human, not rodent, data, predicts alternatives to soon replace whole-animal tests; ECHA sees “long-way” until regulatory acceptance of alternatives for complex endpoints
August 18, 2017
Utility of bioassays in safety assessment
Scientists demonstrate utility of bioassays in FCM safety assessment using 4-nonylphenol (4NP) as model substance; 4NP levels detected by bioassays considered relevant for safety assessment
June 2, 2017
In vitro testing of paper and board FCMs
Scientists test paper and board FCMs in 8 in vitro bioassays; all 20 samples showed positive responses in at least one of the assays; chemicals in paper and board FCMs require further investigation to ensure safety
