Scientists demonstrate utility of bioassays in FCM safety assessment using 4-nonylphenol (4NP) as model substance; 4NP levels detected by bioassays considered relevant for safety assessment
July 21, 2017
High throughput in vitro testing of BPA analogues
Scientists analyze estrogen- and androgen-like properties of BPA analogues using cell-based high throughput microscopy-employing tests; demonstrate anti-estrogenic and anti-androgenic properties of TMBPF
July 14, 2017
In vitro testing of FCMs: Current science and future challenges
New scientific study by FPF summarizes research on alternative toxicity testing of FCMs, finds approach promising and feasible; sample preparation methods need to be optimized and standardized; employed assays should be of clear human health relevance
July 7, 2017
Phthalates’ impact on human health
Scientists compile comprehensive review on phthalates, focus on human health effects observed in epidemiological and clinical studies
June 9, 2017
Genotoxic chemicals in coatings
Scientists compile inventory of compounds potentially used in coatings; 1,976 substances have no (recent) toxicological evaluation; subset analyzed by in silico tools and literature search, 10 compounds designated as ‘high concern’
June 2, 2017
In vitro testing of paper and board FCMs
Scientists test paper and board FCMs in 8 in vitro bioassays; all 20 samples showed positive responses in at least one of the assays; chemicals in paper and board FCMs require further investigation to ensure safety
June 2, 2017
DEHP increases BPA exposure
Scientists show that diethylhexyl phthalate (DEHP) leads to higher accumulation of bisphenol A (BPA) in reproductive tissues of mice, likely due to competition for detoxification enzymes
May 31, 2017
New test methods for EDCs needed
JRC expert survey identifies gaps in test methods for evaluating endocrine disruptors; new methods for thyroid, metabolic, immune disorders, as well as hormone-related cancers seen as priority
May 26, 2017
Regulatory acceptance of non-animal tests
U.S. federal agencies’ committee releases draft roadmap for further developmnt of alternative testing approaches, aimed at improving regulatory acceptance; public consultation open until August 31, 2017
May 16, 2017
Hazard assessment of FCM extracts
Scientists review studies on the use of select bioassays to assess hazard of food contact materials; bioassays considered a useful addition to targeted chemical analysis, especially in the assessment of finished materials and articles
