Series of new studies finds mixtures of everyday non-carcinogenic chemicals to be of concern for causing cancer; individual chemicals present at low levels; opportunity for improvement of chemical risk assessment and primary prevention of cancer
Can phthalates make you fat?
New study investigates metabolic effects of DEHP exposure in mice in vivo and in vitro; increased weight gain and fat mass, impaired insulin tolerance and changes in serum metabolites observed
US and France release statement supporting UN plastics treaty
At the One Ocean Summit on February 10, the United States and France delivered a joint statement supporting a global plastics treaty; agree treaty should address whole lifecycle of plastics and include binding commitments
Uptake and internal distribution of PFAS
Scientists develop radiolabeling method to trace per- and polyfluoroalkyl substances (PFAS) uptake and distribution in mice; observe uptake in all organs, transport from mother to fetus across placenta; highest uptake in liver after tail vein administration, in lungs after oral gavage
How mothers’ environment affects grandchildren
New study observes disease inheritance across generations, but finds epigenetic changes not to persist
Scientific consensus on endocrine disruptors
Scientists reach agreement on scientific principles underpinning the identification of EDCs at expert meeting in Berlin; meeting report to be published soon
Germany: Increasing safety along the food chain
German Institute for Risk Assessment announces cooperation with Fraunhofer Institutes to increase safety along the food chain
Migration of cyclo-di-BADGE into oily foods
German Federal Institute for Risk Assessment evaluates migration of NIAS cyclo-di-BADGE from can coatings into oily fish; suggests TTC of 90 µg/person/day and generating more toxicity data
Scientists reach consensus on EDCs
Scientists agree that potency should not be included in the EU’s criteria for EDCs; NGOs call on European Commission to adopt scientific consensus and release EDC criteria promptly
Decision matrix for EDCs
German Federal Institute for Risk Assessment proposes extended assessment criteria to identify endocrine disruptors under European regulation