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First proposals put forward for global treaty to end plastic pollution

Countries are submitting proposals to the UN Environment Program to guide Plastics Treaty development; US proposes treaty focus on downstream effects – reuse and recycling; proposal from 40-nation ‘high ambition coalition’ proposes setting up limits on polymer production, eliminating certain polymers and products; over 60 proposals received so far; stakeholder registration is open for the next negotiating meeting for the Plastics Treaty in Paris, France in May 2023

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Scientists explore effects of micro- and nanoplastics on mammals, including humans

Research studies show maternal polystyrene (PS) particle exposure can cause testicular and hepatic toxicity in male mouse offspring; report PS microplastics affect rat ovary function; find correlation between human fecal microplastics levels and Inflammatory Bowel Disease; reviews summarize potential human health effects; study develops a tool to screen and prioritize micro-and nanoplastics toxicity studies for human health risks evaluation

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Microplastics impacts on the reproductive system and offspring

Scientists report human-relevant polystyrene (PS) microplastic concentrations change mice placental metabolism; show nanoplastics have variable effects on placental enzymes using simulations; find pre- and postnatal PS microplastic exposure affects male mice testis development and fertility; recommend future research to analyze multigenerational effects