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Plastic Soup Foundation launches “Plastic Health” web series discussing latest scientific evidence; announces publication of expert opinions, interviews on hazards of microplastics, nanoplastics, and additives
PAN Europe warns of using Adverse Outcome Pathway (AOP) as prediction tool; ECETOC sees AOP’s potential in assessing EDCs
Article published in Science lays out key knowledge gaps hindering human health risk assessments of microplastics, highlights lack of analytical tools to assess small microplastics and nanoplastics; estimated low exposure does not imply low risk
Parabens inhibit several biotransformation enzymes involved in steroid hormone metabolism and chemical detoxification; study in mice shows that co-exposure with butyl paraben results in elevated internal levels of estradiol and BPA
Three studies investigate micro- and nanoplastics – source, organ deposition, and reproductive effects; detect up to 240,000 plastic particles/L in bottled water with 90% being nanoplastics; find microplastics in human lung, intestine, and kidney tissues; polyethylene particles found to affect placental function in mice
The Threshold of Toxicological Concern, short TTC, is a concept for assessing the risk of single chemical exposure to human health. It establishes generic exposure thresholds based on chemical structure below which chemicals are assumed to be safely used. In the absence of toxicological data, regulators, academic scientists and industry experts are using the TTC to perform chemical risk assessments. On October 17, 2013 the Food Packaging Forum held a workshop offering a platform for balanced information and scientific debate […]
Two in vitro studies analyze plastic particle effects using human cells; find polystyrene (PS) particles change metabolism of human colon cells similar to a carcinogen; PS nanoplastics may have cytotoxic and genotoxic potential on human blood lymphocytes; mouse study indicates microplastics increase risk of insulin resistance; researchers calculate particle ingestion from takeaway containers
Scientific study compares accumulation of mineral oil saturated hydrocarbons (MOSH) in rats to humans; findings imply that current acceptable daily intake for MOSH may be set too high and current human exposure is underestimated
Review summarizes microplastics abundance and characteristics in human biological samples including current research approaches employed, challenges, and prospects; study indicates microplastics impact human meconium and placenta microbiota; review outlines current evidence on microplastic effects upon exposure during early developmental stage
Mice study shows that co-exposure with tetrabromobisphenol A and triclosan alters toxicokinetics of BPA, results in elevated tissue levels
