EFSA supports research on AOPs

Call for research proposals on adverse outcome pathways identifying new endocrine disrupting chemicals research, focus on uterine adenocarcinoma; proposals to be submitted to European Food Safety Authority until September 14, 2020

FCM-relevant AOP research

Scientists explore adverse outcome pathways (AOPs) associated with bisphenols, phthalates, perchlorate, food additives, microplastics; discuss ways of using AOPs to predict chemical hazards, assess mixture toxicity

OECD webinar on AOP knowledge base

Organisation for Economic Co-operation and Development (OECD) to host webinar on using Adverse Outcome Pathway Knowledgebase (AOP-KB) on January 30, 2020; provide technical tips for submitting and retrieving scientific information on AOPs

Survey on adverse outcome pathways

EU Commission’s Joint Research Centre opens survey on adverse outcome pathways, aims to improve use of AOP framework and resources, understand further development needs to enable regulatory use

Testing for developmental neurotoxicity

Special issue of Toxicology and Applied Pharmacology features 18 articles discussing alternative (non-animal) methods for assessing chemicals’ potential to harm neurodevelopment in children

AOPs in Integrated Approaches to Testing and Assessment

OECD publishes guidance on the use of Adverse Outcome Pathways (AOPs) in developing Integrated Approaches to Testing and Assessment (IATA); AOPs to support chemical grouping, development of models, test methods, and testing strategies, and interpretation of test results

Two perspectives on Adverse Outcome Pathways

PAN Europe warns of using Adverse Outcome Pathway (AOP) as prediction tool; ECETOC sees AOP’s potential in assessing EDCs