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FCM-relevant AOP research

Scientists explore adverse outcome pathways (AOPs) associated with bisphenols, phthalates, perchlorate, food additives, microplastics; discuss ways of using AOPs to predict chemical hazards, assess mixture toxicity

FDA colloquium on in silico methods

Society of Toxicology and U.S. Food and Drug Administration host event on in silico testing methods; presentations focus on drivers for acceptance and treatment of uncertainties

JRC: 2018 report on alternatives to animal testing

Joint Research Centre publishes annual 2018 report on ‘recent achievements and future plans’ in the field of development and regulatory acceptance of alternative approaches to animal testing

Testing for developmental neurotoxicity

Special issue of Toxicology and Applied Pharmacology features 18 articles discussing alternative (non-animal) methods for assessing chemicals’ potential to harm neurodevelopment in children

FPF Webinar on prioritizing potential genotoxics in FCMs

Register now for the Food Packaging Forum’s webinar on prioritization of potentially genotoxic substances in printed paper and board food contact materials, to be held on November 26, 2018

Mechanistic data in hazard assessment

Academic and industry scientists debate whether use of mechanistic data in regulatory hazard assessment of chemicals should be decisive or supportive only, discuss study selection process for systematic reviews

Computational method outperforms animal tests

Predictions of acute health hazards by ‘data fusion’ read-across structure activity relationship (RASAR) modeling reported to be more reproducible than animal testing data

Performance of in silico models for mutagenicity

Scientists evaluate performance of 4 in silico models to predict mutagenicity of food contact chemicals; applicability domain important, sensitivity for new substances poor

Alternative toxicity testing in the U.S.

U.S. EPA publishes draft strategy for use of alternative toxicity tests in evaluation of chemicals under updated chemicals regulation

FPF Workshop 2018: Save the date!

Food Packaging Forum holds 6th annual workshop on October 4, 2018 in Zurich, Switzerland; first speakers and topics confirmed

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