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JRC: 2018 report on alternatives to animal testing

Joint Research Centre publishes annual 2018 report on ‘recent achievements and future plans’ in the field of development and regulatory acceptance of alternative approaches to animal testing

Testing for developmental neurotoxicity

Special issue of Toxicology and Applied Pharmacology features 18 articles discussing alternative (non-animal) methods for assessing chemicals’ potential to harm neurodevelopment in children

FPF Webinar on prioritizing potential genotoxics in FCMs

Register now for the Food Packaging Forum’s webinar on prioritization of potentially genotoxic substances in printed paper and board food contact materials, to be held on November 26, 2018

Ames test insufficient for genotoxicity of FCMs

Scientists deem Ames test unsuitable as standalone method to evaluate genotoxicity of FCM migrates, suggest complementing it with chemical information

FCM analysis at BioDetectors conference 2018

11th BioDetectors conference addresses use of cell-based bioassays in food contact material safety analysis

Mechanistic data in hazard assessment

Academic and industry scientists debate whether use of mechanistic data in regulatory hazard assessment of chemicals should be decisive or supportive only, discuss study selection process for systematic reviews

Progress in high-throughput in vitro testing

In vitro assays and alternative approaches being developed for EPA’s Endocrine Disruptor Screening Program and within EU-ToxRisk are hitting ground

Alternative toxicity testing in the U.S.

U.S. EPA publishes draft strategy for use of alternative toxicity tests in evaluation of chemicals under updated chemicals regulation

Alternative plasticizers adipogenic in vitro

Several alternative plasticizers used in FCMs shown to promote lipid accumulation in vitro; direct activation of PPARγ suggested as possible mechanism

In vitro tests for toxicological profiling of FCMs

In vitro assays demonstrate significant biological activity in extracts from diverse food contact articles made of paper and board; bioassays expected to become accepted tool for assessment of FCM safety

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