Two in vitro studies analyze plastic particle effects using human cells; find polystyrene (PS) particles change metabolism of human colon cells similar to a carcinogen; PS nanoplastics may have cytotoxic and genotoxic potential on human blood lymphocytes; mouse study indicates microplastics increase risk of insulin resistance; researchers calculate particle ingestion from takeaway containers
Microplastics measured in human blood and mouse brains
First human biomonitoring study encounters plastic particles of four different polymer types in human blood; in vivo study reports polystyrene nanoparticles pass blood-brain barrier and induce neurotoxicity in mice; review summarizes plastic particle and titanium dioxide impacts on human gut epithelial integrity, gut homeostasis, and intestinal inflammation
Microplastics may affect the human microbiome
Scientists explore potential impacts of microplastics on human intestine ecology; microplastics may drive unhealthy changes in the gut microbiome; authors highlight importance of assessing human microplastics exposure and hazards for the gut
Chemicals change gut microbiome in children
Study in Environmental Science Technology Letters investigates presence of semi-volatile organic chemicals (SVOCs) and associated changes in microbiome of 79 children with 43 SVOC biomarkers detected; study includes phthalates, phenols, per- and polyfluoroalkyl substances (PFAS); less abundant microbes replaced due to higher sensitivity to chemicals, increased abundance of dehalogenation bacteria observed; more extensive studies needed to verify results and understand human health implications
Microplastics affect gut function and microbiota
Scientists find chronic exposure of mice to polystyrene microplastics affects intestinal barrier function, gut microbiota composition, metabolic indices