Study identifies mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) exposure as high-risk factor for leiomyoma growth on epidemiological and mechanistic level; European biomonitoring of five reprotoxic phthalates demonstrates necessity to integrate mixture risk assessment into regulatory practice; targeted analysis shows migration of five phthalates from polypropylene food packaging
Study detects DNA-reactive, mutagenic substances in recycled PE, PP, and PS
119 plastic samples including polyethylene (PE), polypropylene (PP), polystyrene (PS), and polyethylene terephthalate (PET) tested for mutagenicity; no DNA-reactive, mutagenic substances in PET but in 51 of the other samples, making them unsafe, especially for food contact applications; recycling process identified as source; dataset of over 600 organic chemicals in recycled high-density PE pellets published
New study identifies candidates for hormonal activity in bottled waters
Antiestrogenic substance di(2-ethylhexyl) fumarate identified in retail samples, origin of contamination remains unclear
New research on chemical migration from plastic, paper, can coating, and reusables
Recent reports investigate whitening agents’ migration from disposable plastic containers; characterize 153 chemicals migrating from paper packaging and show estimated dietary exposure for children to per- and polyfluorinated alkyl substances (PFAS) exceed safety threshold; detect brominated flame retardants in repeat-use food contact articles; review metal can coating literature concerning coatings types, chemical migrants, detection methods, dietary exposure, and regulatory
Testing finds antimony in common beverages bottled in PET
Study carried out by Defend Our Health detects antimony above safe levels in 40% of tested beverages sold in PET bottles; antimony widely used as a catalyst to produce PET; calls on manufacturers to switch to widely available safer chemical alternatives, address the numerous hazardous substances that can migrate from plastics into food, chemical pollution in communities surrounding production sites
An introductory guide to EDCs
Endocrine society and NGO network released a new guide providing a comprehensive introduction to EDCs
ECHA updates guidance on SVHCs in articles
ECHA publishes comprehensive update of guidance on substances of very high concern in articles, clarifies companies’ communication and notification obligations
Phthalates in vinyl gloves
Study by NGO Ecology Center finds ortho-phthalates in vinyl gloves used to handle food, urges use of alternatives such as washed bare hands, polyethylene or nitrile gloves
RIVM studies argue applied maximum doses too low
Researchers from Dutch National Institute for Public Health and the Environment (RIVM) publish two peer-reviewed articles critically reviewing determination and application of maximum doses in toxicity studies; find that recent toxicity studies increasingly using unjustified low maximum doses, call for more clarity in testing guidelines
Can phthalates make you fat?
New study investigates metabolic effects of DEHP exposure in mice in vivo and in vitro; increased weight gain and fat mass, impaired insulin tolerance and changes in serum metabolites observed