In an article published on April 29, 2016 the National Food Institute at the Technical University of Denmark (DTU Food) informs about a new project aiming to develop quantitative structure-activity relationship (QSAR) models to screen and prioritize substances potentially affecting thyroid hormones. Thyroid hormones play an important role in metabolic processes and in early-life brain development, DTU Food explains. The researchers developing the models will use experimental testing data made available by American collaboration partners. The new models will be used to screen over 600,000 substances, including around 70,000 substances potentially available on the European market. The predictions will be made publically available in DTU Food’s QSAR database (FPF reported). Using these new models can help minimize the need for laboratory animal testing and contribute to the development of safer drugs and chemicals, DTU states.
DTU Food (April 29, 2016). “Using computers to detect more endocrine disrupting chemicals.”