On August 4, 2014 the French National Institute for Agricultural Research (INRA) published a press release on a study showing that perinatal low dose exposure to bisphenol A (BPA) increases the risk of food intolerances in adulthood. INRA states in the press release that the findings support the French decision to ban BPA from all food packaging by 2015 (previously reported on by the FPF). In their study the researchers from INRA’s Joint Research Unit for Food Toxicology (TOXALIM) in Toulouse, France exposed rats to different doses of BPA (0.5, 5 and 50 µg/kg body weight (bw)/day) both prenatally and during suckling. Rats exposed to 5 µg/kg bw/day showed an immune reaction, and inflammation of the colon, when fed an egg white protein at 45 days of age. The inflammation of the colon is considered a biomarker of food intolerance. In the press release, INRA states that methods used in the study may be used to investigate effects of other endocrine disruptors on the immune system, in particular of BPA alternatives.

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INRA (August 4, 2014). “Bisphenol A and food intolerance, a link established for the first time.”