In an article published on August 23, 2018, by the National Food Institute (DTU Food) of the Technical University of Denmark, Miriam Meister reported that the Organisation for Economic Co-operation and Development (OECD) updated its test guideline 414 on prenatal development toxicity. The update was adopted by the OECD in spring 2018 and published online on June 27, 2018.

Researchers from DTU Food helped improve the guideline which now includes “an examination of the distance between anus and genitals (anogenital distance) and a more thorough study of genital deformities in the fetuses as well as the mothers’ thyroid hormones,” Meister informed. The test now detects more endocrine disrupting chemicals (EDCs) and provides “more knowledge about possible endocrine disrupting effects without using more test animals than is already required,” Meister further explained.

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Miriam Meister (August 23, 2018). “Unborn children better protected against endocrine disruptors.DTU Food


OECD (June 27, 2018). “Test No. 414: Prenatal development toxicity study.OECD guidelines for the testing of chemicals, section 4: Health effects