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U.S.: Discordance on self-affirmed GRAS substances

Lack of information for self-affirmed GRAS (generally recognized as safe) substances has been highlighted by scientists of the public interest group PEW Charitable Trust in the US. Now the industry reacts by making available a database with manufacturers self-determined GRAS substances, used in food contact materials and/or food. Critics maintain that this effort is insufficient, and that a proper safety assessment needs to be carried out by the regulator instead.

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German authorities seek comments for bisphenol restriction proposal

Federal Institute for Occupational Safety and Health, the competent authority for REACH in Germany, and the German Environment Agency launch second stakeholder consultation in preparation for a REACH Restriction Dossier for bisphenol A (BPA) and other similar bisphenols; seeking updated use information including tonnages, emissions, alternatives and transition costs, and limit values; authorities already have enough data to demonstrate hazards

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Phthalates: impact on leiomyoma growth and mixture risk

Study identifies mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) exposure as high-risk factor for leiomyoma growth on epidemiological and mechanistic level; European biomonitoring of five reprotoxic phthalates demonstrates necessity to integrate mixture risk assessment into regulatory practice; targeted analysis shows migration of five phthalates from polypropylene food packaging

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Microplastics may affect the human microbiome

Scientists explore potential impacts of microplastics on human intestine ecology; microplastics may drive unhealthy changes in the gut microbiome; authors highlight importance of assessing human microplastics exposure and hazards for the gut