Two EU funded research projects investigating chemical mixtures hold joint stakeholder workshop to present results, call for better consideration of mixtures in regulatory risk assessment and provide open-source tools for future research
EFSA publishes mixtures methodology
European Food Safety Authority launches guidance on assessment of ‘combined effects’ of chemical mixtures in food and feed
EFSA: Genotoxicity of mixtures
European Food Safety Authority publishes statement on genotoxicity assessment of chemical mixtures
Toxic effects of MOSH exposure
Dietary exposure of rats to mineral oil saturated hydrocarbons (MOSH) fractions similar to those accumulating in humans causes increase of liver and spleen weights; clinical significance needs further investigation
Science and practice of mixture assessment
Scientific means to assess chemical mixtures are available, but regulatory application lags behind due to practical challenges and lack of legal mandates
Canada to update chemicals management
Canadian public health department opens public consultation to define ‘vulnerable populations,’ aims to improve chemicals management with future consultations on endocrine disruptors and mixture toxicity
New EFSA FCM working group: 1st meeting
EFSA’s CEP Panel working group on food contact materials holds 1st meeting; minutes now available online
Ames test insufficient for genotoxicity of FCMs
Scientists deem Ames test unsuitable as standalone method to evaluate genotoxicity of FCM migrates, suggest complementing it with chemical information
Risks of combined exposure to EDCs
Scientists use real-life exposure data to identify EDC mixtures associated with health outcomes, demonstrate that combined exposure to multiple EDCs results in effects not observed with single chemicals at similar levels
FCM analysis at BioDetectors conference 2018
11th BioDetectors conference addresses use of cell-based bioassays in food contact material safety analysis