OECD endorses five new Adverse Outcome Pathways; cover liver fibrosis, heritable mutations, reproductive dysfunction, impairment of learning and memory abilities in children and adults; new background article on AOPs available on FPF website
October 17, 2016
Adverse outcome pathways
Adverse outcome pathway (AOP) describes the sequence of events linking initial molecular perturbations to adverse outcomes in organisms and populations; this framework supports the use of high-throughput animal-free toxicity testing methods in regulatory decision-making
October 7, 2016
Non-target screening of silicone rubber extracts
Scientists perform non-target screening of compounds extracted from infant silicone teats; identify 140 compounds in 12 categories; more than a third of substances need safety evaluation
September 22, 2016
BfR Annual Report 2015 released
Annual Report 2015 of the German Federal Institute for Risk Assessment (BfR) includes topics relevant to food contact materials and human health, e.g. silver nanoparticles, microplastics
September 22, 2016
Danish environment minister comments on EDC criteria
Esben Lunde Larsen appreciates effort, but criticizes outcome of EC’s criteria on endocrine disrupting chemicals; proposes two category approach identifying confirmed and suspected EDCs
September 20, 2016
BfR’s research on nanomaterials
German Institute for Risk Assessment (BfR) summarizes its research on health and environmental safety of nanomaterials and other novel materials; nanoparticle detection optimized in different matrices; animal-free toxicity testing implemented
September 19, 2016
Opinion: EDC criteria and potency
Scientists for Scientific European Commission Regulation publish opinion on the European Commission’s criteria for endocrine disrupting chemicals (EDCs); call for potency to be an aspect of regulatory EDC identification in line with industry views but not supported by the Endocrine Society
September 16, 2016
Endocrine-active chemicals in baby bottles
Scientists test 65 chemicals migrating from ‘BPA-free’ baby bottles in a panel of in vitro assays for effects on seven receptors; 12 chemicals show no activity, 53 activate or inhibit at least one of the tested receptors
September 13, 2016
EU Commission’s Working Group on FCMs
EU Working Group on FCMs discusses BPA, amendments to EU 10/2011, mineral oil migration, authorization of recycling processes, migration testing guidelines
September 9, 2016
Health risks of ‘BPA-free’ baby bottles
Scientists evaluate health risks of migrants from ‘BPA-free’ baby bottles made of PP, PA, PES, silicone, Tritan™, stainless steel; silicone bottle, several PP bottles of ‘high concern’; Tritan™ bottle, several more PP bottles of ‘concern’
