JRC proposes improved testing strategies

EU’s Joint Research Centre (JRC) publishes study identifying chemical testing strategies that require fewer tests, reduce need for animal testing; based on data on biocide and plant protection products, could be expanded for use across other product types

‘The trouble with plastics’

Special issue of peer-reviewed journal Birth Defects Research presents a collection of articles on plastics’ effects on human health, with a particular focus on early development

Clarifications to REACH data requirements

European Commission publishes draft amendment to REACH text dealing with information requirements for chemicals dossiers; feedback accepted until November 16, 2020

Recent studies on EDCs and cardiovascular health

Emerging evidence and systematic analyses highlight adverse effects of bisphenols and phthalates on cardiovascular health; meta-analysis of US National Health and Nutrition Examination Survey data from 2003-2016 finds significant association of cardiovascular disease with bisphenol A; prenatal exposure particularly detrimental; calls for more mechanistic research, evaluation of cardiovascular safety profiles for substitution chemicals

New York Times investigates PFAS and pregnancy

Publishes second article in three-part series on hazardous chemical exposure at home; provides overview of research on toxicity of per- and polyfluoroalkyl substances (PFAS) to developing fetuses, young children; profiles US families with high PFAS concentrations in drinking water, efforts to restrict uses

In vitro toxicity of bioplastics and plant-based materials

Scientists investigate in vitro toxicity of extracts from bioplastics and plant-based food contact articles; find strongest toxicity induced by cellulose- and starch-based products; emphasize similar toxicity profiles among bio-based, biodegradable, and conventional plastics

Combined evidence supports low-dose effects of BPA

Scientists integrate and interpret data from 8 of the 14 academic studies completed under the CLARITY-BPA project; link bisphenol A (BPA) exposure to impacts across multiple organs including brain, heart, prostate, mammary gland, ovaries; strengthen confidence in low-dose effects of BPA; co-authors to present results in webinar on July 21, 2020

ECHA report on alternatives to animal testing

Fourth report from the European Chemicals Agency (ECHA) finds little change since 2017, number of alternative testing adaptations continuing to increase; read-across most commonly applied followed by data-waiving and weight of evidence approaches

Webinar on key characteristics of hazardous chemicals

Food Packaging Forum holds webinar with presentation from Martyn Smith on the identification of key characteristics to support chemical evaluation; introduces concept and recent key publications; recording now available to watch

Webinar on computational predictive toxicology projects

American Society for Cellular and Computational Toxicology (ASCCT) to hold webinar on May 26, 2020, discussing three recently completed projects developing collaborative in silico toxicology models