Special issue of Toxicology and Applied Pharmacology features 18 articles discussing alternative (non-animal) methods for assessing chemicals’ potential to harm neurodevelopment in children
India bans PET for certain pharmaceuticals
India phases out PET and other plastic bottles as packaging for medicinal products for pediatric, geriatric use and for use by women in the reproductive age
Parabens increase BPA exposure
Parabens inhibit several biotransformation enzymes involved in steroid hormone metabolism and chemical detoxification; study in mice shows that co-exposure with butyl paraben results in elevated internal levels of estradiol and BPA
Nordic Council checks compliance of products sold online
Inspectors from Nordic countries examine 361 products ordered online for compliance with various EU chemicals legislation; find 53% non-compliant, higher rate of non-compliance for products sold by companies outside of EU; lead, short chain chlorinated paraffins, diethylhexyl phthalate (DEHP) detected most often
IARC replies to critiques
IARC scientists reply to critical commentary; point out the importance of hazard classification as an initial step in the risk assessment process, highlight the role of epidemiological evidence
EU observatory for nanomaterials now online
ECHA launches European Union Observatory for Nanomaterials website; provides information on nanomaterials on the EU market for consumers, workers, regulators, and scientists
New PLA production technology
Dutch scientists develop technology to make production of bioplastic PLA faster and cheaper
Review of technologies for PHA production
Scientists review three main routes for polyhydroxyalkanoates (PHA) production, including microbiological, enzymatic, chemical; microbiological and chemical routes most favorable for scaling-up; remaining high costs compared to fossil-based plastics necessitate search for cheaper feedstocks, optimization of production efficiencies
BPA absorption in the mouth
Scientists compare internal levels and metabolism of BPA after gavage or diet administration; demonstrate significant buccal absorption of BPA from solid foods
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