CLARITY-BPA study finds BPA exposure to increase incidence and severity of cardiomyopathy, promoting myocardial degeneration; BPA’s cardiotoxicity could be caused by adverse vascular events
March 24, 2017
AOPs in Integrated Approaches to Testing and Assessment
OECD publishes guidance on the use of Adverse Outcome Pathways (AOPs) in developing Integrated Approaches to Testing and Assessment (IATA); AOPs to support chemical grouping, development of models, test methods, and testing strategies, and interpretation of test results
March 17, 2017
Reference guide on health effects of chemicals
Integrative Environmental Medicine book provides comprehensive overview of chemical effects on health, outlines resources and tools helping to reduce exposure and risks
March 9, 2017
MigraTox: Optimizing in vitro testing of FCMs
Austrian Research Institute for Chemistry and Technology (OFI) initiates MigraTox project to work on optimizing and standardizing sample preparation and bioassays for in vitro testing of food contact materials; focuses on genotoxicity assays; calls on industrial partners to collaborate and provide samples
March 1, 2017
Fluorene-9-bisphenol is anti-estrogenic
Scientists examine occurrence and effects of bisphenol A substitute, fluorene-9-bisphenol (BHPF); BHPF present in about half of ‘BPA-free’ bottles; BHPF is anti-estrogenic, causes smaller wombs, miscarriages, and smaller pups in mice
February 24, 2017
Lack of ‘nano’ in OECD nanomaterials dossiers
NGO-commissioned study finds that OECD’s dossiers on 11 nanomaterials are of ‘little to no value’ in assessing risks; characterization of test materials in most cases ‘insufficient’ to ensure nano-specificity
February 24, 2017
BPA and autoimmune disorders
Scientists report evidence suggesting that immune reactivity to BPA bound to human tissue proteins may contribute to neurological autoimmune disorders
February 24, 2017
Antiandrogenic chemicals in food
Scientists review food components and contaminants that can act as (anti)androgens; in vitro-based computational model for interactions with androgen receptor identifies active chemicals in ToxCast dataset
February 23, 2017
EFSA study: Bioaccumulation and toxicity of mineral oils
New EFSA scientific study tests different mixtures of mineral oil saturated hydrocarbons (MOSH), relevant to human diet, in rats; bioaccumulation at low dose MOSH exposure in humans possibly underestimated; MOSH appear persistent in adipose tissue
February 13, 2017
In vitro bioassays for FCMs
Austrian research institute for chemistry and technology holds information event on bioassays for food contact materials on March 8, 2017 in Vienna
