Ana Soto presents biological mechanisms underlying non-monotonic dose-responses, explains why non-monotonicity is ‘useful to organisms, challenging for regulators,’ discusses CLARITY-BPA’s successes and limitations
Using high-throughput screening data in FCM assessment
ILSI North America publishes case studies comparing U.S. EPA in vitro ToxCast data with in vivo toxicity data for food contact chemicals, identifies potential as well as challenges integrating high-throughput screening data into safety assessments
New BfR statement on polyamide oligomers
German risk assessment institute uses newly received toxicity data to establish group migration limit of 5mg/kg food for PA6 and PA66 oligomers
Webinar on chemicals in plastic consumer products
Lisa Zimmerman from PlastX project to present recent study results in Food Packaging Forum webinar on September 24, 2019; study investigates in vitro toxicity and chemical composition of plastic consumer products
Benchmarking in vitro toxicity of plastics
Scientists investigate in vitro toxicity and chemical composition of plastic consumer products made of different polymers; high baseline toxicity of polylactic acid (PLA) bioplastics; food contact status does not necessarily imply lower toxicity
Survey on adverse outcome pathways
EU Commission’s Joint Research Centre opens survey on adverse outcome pathways, aims to improve use of AOP framework and resources, understand further development needs to enable regulatory use
France bans TiO2 in food
France bans titanium dioxide in food by 2020 following report by ANSES reiterating 2017 recommendation to reduce exposures; EFSA does not see need to open reassessment at the moment
U.S. NGO requests ‘moratorium’ on new PFAS
U.S. NGO Public Employees for Environmental Responsibility (PEER) calls on Congress to halt the introduction of new per- and polyfluoalkyl substances on the market until more is known about their toxicity and persistence; calls for more studies of cancer risks
Recycled plastics in food contact applications
Smithers Pira publishes white paper discussing use of recycled plastics in food contact applications
JRC: 2018 report on alternatives to animal testing
Joint Research Centre publishes annual 2018 report on ‘recent achievements and future plans’ in the field of development and regulatory acceptance of alternative approaches to animal testing